OSBPL1A

Across TCGA patient cohorts, OSBPL1A RNA expression is significantly associated with the protein abundance of many other proteins, with 16,593 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSBPL1A-associated proteins across cancer lineages are IMPACT, DDAH1, and FNDC3B. Each is linked with OSBPL1A in more than 5 cancer types. Because this analysis shows association rather than direction, both OSBPL1A-to-partner and partner-to-OSBPL1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL1A versus IMPACT in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL1A→partner) and Y-score (partner→OSBPL1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IMPACT →	+0.434	+0.796	<.001	<.001	3	6
BRCA	DDAH1 →	+0.564	+0.739	<.001	<.001	3	5
GBM	FNDC3B →	-0.413	-0.447	<.001	.003	3	5
CCRCC	TMED9 →	-0.349	-0.567	<.001	<.001	3	5
GBM	HSP90B1 →	-0.464	-0.658	<.001	<.001	3	5
LSCC	MANF →	-0.469	-0.522	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,593 associations by consensus.

OSBPL1A vs IMPACT — BRCA

Explore this scatter interactively →