OSBPL1A

Across TCGA patient cohorts, OSBPL1A protein abundance is significantly associated with the RNA expression of many other genes, with 7,485 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OSBPL1A-associated genes across cancer lineages are CABYR, C7, and JAM2. Each is linked with OSBPL1A in more than 4 cancer types. Because this analysis shows association rather than direction, both OSBPL1A-to-partner and partner-to-OSBPL1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OSBPL1A versus CABYR in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBPL1A→partner) and Y-score (partner→OSBPL1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CABYR →	+1.110	+0.409	<.001	<.001	3	5
OV	C7 →	+1.778	+0.325	.005	.009	3	4
UCEC	JAM2 →	+0.748	+0.247	.002	.003	3	4
HNSC	MYL3 →	+1.454	+0.245	<.001	<.001	3	4
HNSC	RNU6-435P →	+0.676	+0.164	.001	.002	2	5
OV	IL21R →	-0.895	-0.552	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,485 associations by consensus.

OSBPL1A vs CABYR — BRCA

Explore this scatter interactively →