Across TCGA patient cohorts, OSBP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,357 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OSBP2-associated proteins across cancer lineages are SP100_S18, OSBP2_S284, and ZNF687. Each is linked with OSBP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both OSBP2-to-partner and partner-to-OSBP2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBP2→partner) and Y-score (partner→OSBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SP100_S18 →	-0.345	-0.654	<.001	.003	3	4
GBM	OSBP2_S284 →	+1.278	+1.113	.009	.002	2	5
LSCC	ZNF687 →	+0.392	+0.797	<.001	<.001	3	4
BRCA	EIF4ENIF1 →	+0.205	+0.546	<.001	<.001	3	4
BRCA	ARVCF →	+0.352	+0.456	<.001	.002	3	3
LSCC	CSTF1 →	+0.189	+0.686	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,357 associations by consensus.

Exploration

OSBP2 survival (RNA) · tumor vs normal (RNA) · all OSBP2 data types