Across TCGA patient cohorts, OSBP2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,790 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OSBP2-associated genes across cancer lineages are HBA1, LINC01088, and EIF4HP2. Each is linked with OSBP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OSBP2-to-partner and partner-to-OSBP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBP2→partner) and Y-score (partner→OSBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HBA1 →	+0.967	+0.512	<.001	<.001	3	3
LUAD	LINC01088 →	+0.684	+0.225	<.001	.003	3	3
OV	EIF4HP2 →	+0.920	+0.722	<.001	.001	3	3
BRCA	SLC35E4 →	+0.385	+0.409	.007	.002	3	2
LUAD	TTL →	-0.535	-0.268	<.001	.001	3	2
HNSC	NFATC1 →	-0.930	-0.715	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,790 associations by consensus.

Exploration

OSBP2 survival (RNA) · tumor vs normal (RNA) · all OSBP2 data types