Across TCGA patient cohorts, OSBP2 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,514 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible OSBP2-associated proteins across cancer lineages are ADD2_S455, FBXO7, and ANK1_T1378. Each is linked with OSBP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OSBP2-to-partner and partner-to-OSBP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBP2→partner) and Y-score (partner→OSBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ADD2_S455 →	+1.579	+0.512	<.001	<.001	3	4
CCRCC	FBXO7 →	+0.591	+0.683	<.001	<.001	3	4
CCRCC	ANK1_T1378 →	+1.239	+0.510	<.001	<.001	3	4
CCRCC	DMTN →	+0.602	+0.419	<.001	<.001	3	4
CCRCC	EPB41 →	+0.865	+0.588	<.001	<.001	3	4
CCRCC	RNF123 →	+0.550	+0.611	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,514 associations by consensus.

Exploration

OSBP2 survival (RNA) · tumor vs normal (RNA) · all OSBP2 data types