Across TCGA cell cohorts, OSBP2 mutation is significantly associated with the RNA expression of many other genes, with 143 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OSBP2-associated genes across cancer lineages are OR11H1, MYF6, and GOLGA6L6. Each is linked with OSBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OSBP2-to-partner and partner-to-OSBP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OSBP2→partner) and Y-score (partner→OSBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR11H1 →	+0.082	+4.786	<.001	<.001	3	2
SKIN	MYF6 →	+0.028	+4.977	<.001	.007	3	1
SKIN	GOLGA6L6 →	+0.006	+5.415	<.001	.004	3	1
CNS	C1QB →	+0.024	+4.285	<.001	.001	3	1
CNS	OR14C36 →	+0.031	+4.169	<.001	.008	3	1
CNS	PRM3 →	+0.106	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

Exploration

OSBP2 survival (RNA) · tumor vs normal (RNA) · all OSBP2 data types