OS9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OS9 mutation is significantly associated with the RNA expression of many other genes, with 1,638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OS9-associated genes across cancer lineages are MIR103A1, RNU6-1216P, and OR2F1. Each is linked with OS9 in more than 2 cancer types. Because this analysis shows association rather than direction, both OS9-to-partner and partner-to-OS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR103A1 grouped by OS9-low versus OS9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OS9→partner) and Y-score (partner→OS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMIR103A1 →+0.899+4.721<.001.00433
COADRNU6-1216P →+0.753+5.122<.001<.00133
COADOR2F1 →+0.090+4.917<.001.00333
COADMED6P1 →+0.351+4.251<.001.00833
COADRN7SL841P →+0.304+5.734<.001<.00133
COADRN7SL205P →+0.167+4.917<.001.00333
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,638 associations by consensus.

MIR103A1 by OS9 expression — COAD

Box plot of MIR103A1 in OS9-low vs OS9-high samples in COAD.

Explore this box plot interactively →

Exploration