OS9

Across TCGA cell cohorts, OS9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,505 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OS9-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Negative regulation of respiratory burst involved in inflammatory response, and Negative regulation of respiratory burst. Each is linked with OS9 in more than 16 cancer types. Because this analysis shows association rather than direction, both OS9-to-partner and partner-to-OS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multi-pass transmembrane protein insertion into ER membrane grouped by OS9-low versus OS9-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OS9→partner) and Y-score (partner→OS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Multi-pass transmembrane protein insertion into ER membrane →	+0.156	+1.023	.004	.001	2	17
LUNG_SCLC	Negative regulation of respiratory burst involved in inflammatory response →	+0.125	+0.993	.002	<.001	3	16
LUNG_SCLC	Negative regulation of respiratory burst →	+0.125	+0.993	.002	<.001	3	16
PANCREAS	Membrane protein ectodomain proteolysis →	+0.155	+0.955	<.001	<.001	3	15
LUNG_NSCLC_LUAD	Lysosomal transport →	+0.064	+1.088	<.001	<.001	3	15
CNS	Membrane protein proteolysis →	+0.136	+1.022	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,505 associations by consensus.

Multi-pass transmembrane protein insertion into ER membrane by OS9 expression — BLOOD_Myeloma

Explore this box plot interactively →