ORMDL2

Across TCGA patient cohorts, ORMDL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,131 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ORMDL2-associated proteins across cancer lineages are PIP4K2C, PTGES3, and LARP4. Each is linked with ORMDL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ORMDL2-to-partner and partner-to-ORMDL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ORMDL2 versus PIP4K2C in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ORMDL2→partner) and Y-score (partner→ORMDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PIP4K2C →	+0.333	+0.435	<.001	<.001	3	6
LUAD	PTGES3 →	+0.302	+0.368	<.001	<.001	3	6
LUAD	LARP4 →	+0.392	+0.366	<.001	<.001	3	5
COAD	LARP4_S722 →	+0.390	+0.521	<.001	<.001	3	5
BRCA	PYM1 →	+0.334	+0.477	<.001	<.001	3	5
BRCA	MYG1 →	+0.345	+0.356	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,131 associations by consensus.

ORMDL2 vs PIP4K2C — BRCA

Explore this scatter interactively →