ORMDL1

Across TCGA patient cohorts, ORMDL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,112 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ORMDL1-associated proteins across cancer lineages are PRPF4B, PAXBP1, and RIF1. Each is linked with ORMDL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ORMDL1-to-partner and partner-to-ORMDL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ORMDL1 versus PRPF4B in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ORMDL1→partner) and Y-score (partner→ORMDL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRPF4B →	+0.220	+0.479	.002	<.001	3	4
LSCC	PAXBP1 →	+0.178	+0.406	.001	<.001	3	3
LSCC	RIF1 →	+0.566	+0.563	<.001	<.001	3	3
GBM	RNF144A →	-1.349	-0.429	<.001	.002	3	3
PDAC	RPS6_S240 →	-0.650	-0.303	<.001	<.001	3	3
LSCC	SF3B1 →	+0.180	+0.510	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,112 associations by consensus.

ORMDL1 vs PRPF4B — LSCC

Explore this scatter interactively →