Across TCGA patient cohorts, ORM1 mutation is significantly associated with the RNA expression of many other genes, with 1,496 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ORM1-associated genes across cancer lineages are RNA5SP412, PACSIN2, and CDADC1. Each is linked with ORM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ORM1-to-partner and partner-to-ORM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORM1→partner) and Y-score (partner→ORM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.537	+2.230	.001	.005	3	2
UCEC	PACSIN2 →	+0.587	+2.807	<.001	.003	3	2
UCEC	CDADC1 →	+0.383	+3.362	.005	.005	3	2
UCEC	BLOC1S6 →	+0.598	+3.338	.002	.005	3	2
UCEC	POLR1F →	+0.643	+2.839	<.001	.001	3	2
UCEC	PLEKHA8 →	+0.514	+2.593	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,496 associations by consensus.

Exploration

ORM1 survival (RNA) · tumor vs normal (RNA) · all ORM1 data types