Across TCGA cell cohorts, ORM1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ORM1-associated genes across cancer lineages are OR6N1, KRTAP5-6, and KRTAP4-12. Each is linked with ORM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ORM1-to-partner and partner-to-ORM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORM1→partner) and Y-score (partner→ORM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR6N1 →	+0.167	+4.415	<.001	.007	3	1
SKIN	KRTAP5-6 →	+0.068	+4.467	<.001	.004	3	1
BREAST	KRTAP4-12 →	+0.046	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

ORM1 survival (RNA) · tumor vs normal (RNA) · all ORM1 data types