ORAI3

Across TCGA patient cohorts, ORAI3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,449 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ORAI3-associated proteins across cancer lineages are PHKG2, RABEP2, and SPCS3. Each is linked with ORAI3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ORAI3-to-partner and partner-to-ORAI3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ORAI3 versus PHKG2 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ORAI3→partner) and Y-score (partner→ORAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PHKG2 →	+0.286	+0.502	.001	<.001	3	4
BRCA	RABEP2 →	+0.292	+0.541	<.001	<.001	3	4
LSCC	SPCS3 →	-0.437	-0.372	<.001	<.001	3	4
GBM	STX4 →	+0.322	+0.525	<.001	<.001	3	4
PDAC	SUN1 →	+0.363	+0.337	.003	<.001	3	4
UCEC	ELOVL1 →	-0.966	-0.798	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,449 associations by consensus.

ORAI3 vs PHKG2 — GBM

Explore this scatter interactively →