ORAI3

Across TCGA patient cohorts, ORAI3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ORAI3-associated genes across cancer lineages are GMP and Basophils. Each is linked with ORAI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ORAI3-to-partner and partner-to-ORAI3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by ORAI3-low versus ORAI3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORAI3→partner) and Y-score (partner→ORAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GMP →	+0.076	+2.348	.040	.041	3	1
UCEC	Basophils →	+0.199	+3.000	.042	.037	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GMP by ORAI3 expression — UCEC

Explore this box plot interactively →