ORAI3

Across TCGA cell cohorts, ORAI3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,635 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ORAI3-associated GO terms across cancer lineages are Store-operated calcium entry, Proteoglycan catabolic process, and Negative regulation of respiratory burst involved in inflammatory response. Each is linked with ORAI3 in more than 14 cancer types. Because this analysis shows association rather than direction, both ORAI3-to-partner and partner-to-ORAI3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Store-operated calcium entry grouped by ORAI3-low versus ORAI3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ORAI3→partner) and Y-score (partner→ORAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Store-operated calcium entry →	+0.129	+1.580	<.001	<.001	3	15
BONE	Proteoglycan catabolic process →	+0.202	+1.393	.002	.001	3	14
LUNG_SCLC	Negative regulation of respiratory burst involved in inflammatory response →	+0.113	+0.940	<.001	<.001	3	14
LUNG_SCLC	Negative regulation of respiratory burst →	+0.113	+0.940	<.001	<.001	3	14
BONE	Heparan sulfate proteoglycan catabolic process →	+0.176	+1.265	.001	<.001	3	13
OESOPHAGUS	Meiotic chromosome segregation →	-0.152	-1.702	.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,635 associations by consensus.

Store-operated calcium entry by ORAI3 expression — SOFT_TISSUE

Explore this box plot interactively →