ORAI3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ORAI3 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ORAI3-associated genes across cancer lineages are OR10R2. Each is linked with ORAI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ORAI3-to-partner and partner-to-ORAI3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by ORAI3-low versus ORAI3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORAI3→partner) and Y-score (partner→ORAI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR10R2 →+1.283+4.551.006.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR10R2 by ORAI3 expression — BLOOD_Leukemia

Box plot of OR10R2 in ORAI3-low vs ORAI3-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration