ORAI2

Across TCGA patient cohorts, ORAI2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,934 significant associations in total. OV shows the largest number of these associations.

The most reproducible ORAI2-associated genes across cancer lineages are RPL37AP8, NUDT11, and RPL23AP18. Each is linked with ORAI2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ORAI2-to-partner and partner-to-ORAI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ORAI2 versus RPL37AP8 in OV, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORAI2→partner) and Y-score (partner→ORAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RPL37AP8 →	-2.612	-0.913	<.001	.002	3	2
LSCC	NUDT11 →	-0.816	-0.283	.003	<.001	3	2
OV	RPL23AP18 →	-3.105	-1.012	<.001	<.001	3	2
CCRCC	MED8-AS1 →	-0.899	-0.440	.009	.005	3	2
OV	EEF1B2P1 →	-3.082	-0.855	<.001	.008	3	2
OV	WDR90 →	+1.067	+0.790	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,934 associations by consensus.

ORAI2 vs RPL37AP8 — OV

Explore this scatter interactively →