ORAI2

Across TCGA cell cohorts, ORAI2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,631 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ORAI2-associated GO terms across cancer lineages are RNA localization, RNA export from nucleus, and Nuclear export. Each is linked with ORAI2 in more than 14 cancer types. Because this analysis shows association rather than direction, both ORAI2-to-partner and partner-to-ORAI2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by ORAI2-low versus ORAI2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ORAI2→partner) and Y-score (partner→ORAI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	RNA localization →	+0.105	+2.160	<.001	<.001	3	15
BONE	RNA export from nucleus →	+0.110	+0.911	<.001	.002	3	14
SKIN	Nuclear export →	+0.074	+1.267	<.001	.001	3	14
STOMACH	Establishment of RNA localization →	+0.102	+2.455	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Protein depolymerization →	+0.136	+2.355	<.001	<.001	3	14
BONE	Positive regulation of intracellular protein transport →	+0.084	+1.551	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,631 associations by consensus.

RNA localization by ORAI2 expression — STOMACH

Explore this box plot interactively →