ORAI1

Across TCGA patient cohorts, ORAI1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ORAI1-associated genes across cancer lineages are GMP. Each is linked with ORAI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ORAI1-to-partner and partner-to-ORAI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by ORAI1-low versus ORAI1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ORAI1→partner) and Y-score (partner→ORAI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GMP →	+0.121	+3.027	.014	.042	3	2

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GMP by ORAI1 expression — UCEC

Explore this box plot interactively →