OR9Q2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR9Q2 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR9Q2 data layer compared with 12 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher OR9Q2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR9Q2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

UCS, LUAD, and CESC are the cancer types where OR9Q2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSOSMedianAll0.0070.689<.00124view →
LUADDFSMedianIV0.0450.717<.00124view →
CESCOSMedianAll0.1510.798<.00112view →
PAADDFSMedianAll0.1000.484.00312view →
UCECDFSMedianAll1.0000.629.02110view →
SKCMOSMedianIII,IV1.0000.688.0325view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration