Across TCGA patient cohorts, OR9Q1 mutation is significantly associated with the RNA expression of many other genes, with 3,988 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR9Q1-associated genes across cancer lineages are POLR3D, SEC24D, and VPS37A. Each is linked with OR9Q1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR9Q1-to-partner and partner-to-OR9Q1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9Q1→partner) and Y-score (partner→OR9Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLR3D →	+0.456	+3.386	.001	.004	3	4
UCEC	SEC24D →	+0.558	+2.148	.004	<.001	3	3
UCEC	VPS37A →	+0.567	+3.010	<.001	<.001	3	3
UCEC	PAFAH2 →	+0.353	+2.721	.007	.003	3	3
UCEC	DONSON →	+0.578	+2.523	<.001	<.001	3	3
UCEC	WRN →	+0.489	+2.523	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,988 associations by consensus.

Exploration

OR9Q1 survival (RNA) · tumor vs normal (RNA) · all OR9Q1 data types