Across TCGA pan-cancer cohorts, OR9L1P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR9L1P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OR9L1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR9L1P is over-expressed in tumor.
HNSC and KIRC are the cancer types where OR9L1P tumor–normal differential expression is most reproducible.