OR9K2

Across TCGA patient cohorts, OR9K2 mutation is significantly associated with the RNA expression of many other genes, with 1,833 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR9K2-associated genes across cancer lineages are NGRN, RNU6-396P, and H2AC14. Each is linked with OR9K2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR9K2-to-partner and partner-to-OR9K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NGRN grouped by OR9K2-low versus OR9K2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9K2→partner) and Y-score (partner→OR9K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NGRN →	+0.603	+2.332	.001	.003	3	3
SKCM	RNU6-396P →	+0.092	+2.510	.006	.006	3	3
UCEC	H2AC14 →	+0.919	+3.716	<.001	<.001	3	2
UCEC	ILKAP →	+0.360	+3.362	.004	.005	3	2
UCEC	NARF →	+0.469	+2.332	<.001	.003	3	2
SKCM	HPGDS →	-0.457	-3.434	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,833 associations by consensus.

NGRN by OR9K2 expression — UCEC

Explore this box plot interactively →