OR9G4

Across TCGA patient cohorts, OR9G4 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR9G4-associated genes across cancer lineages are ASNS, MEK1, and Akt_pT308. Each is linked with OR9G4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR9G4-to-partner and partner-to-OR9G4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by OR9G4-low versus OR9G4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9G4→partner) and Y-score (partner→OR9G4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.471	+2.584	.002	.010	3	3
UCEC	MEK1 →	+0.553	+3.807	<.001	<.001	3	2
UCEC	Akt_pT308 →	+0.528	+2.321	.048	.034	3	2
UCEC	PCNA →	+0.221	+2.906	.016	.001	2	3
UCEC	S6_pS240_S244 →	+0.515	+2.321	.002	.034	3	2
UCEC	TFRC →	+0.683	+2.222	.002	.011	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

ASNS by OR9G4 expression — UCEC

Explore this box plot interactively →