OR9G4

Across TCGA cell cohorts, OR9G4 mutation is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR9G4-associated genes across cancer lineages are ACOT8, ENG, and HFE. Each is linked with OR9G4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR9G4-to-partner and partner-to-OR9G4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACOT8 grouped by OR9G4-low versus OR9G4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9G4→partner) and Y-score (partner→OR9G4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACOT8 →	-0.617	-3.278	.003	.006	3	1
LARGE_INTESTINE	ENG →	-1.124	-3.278	.003	.006	3	1
LARGE_INTESTINE	HFE →	+0.888	+3.364	.002	.002	3	1
LARGE_INTESTINE	SH3GL2 →	+1.160	+3.667	<.001	<.001	3	1
LARGE_INTESTINE	RNGTT →	+0.484	+3.364	.007	.002	3	1
LARGE_INTESTINE	BAG2 →	+0.938	+3.087	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

ACOT8 by OR9G4 expression — LARGE_INTESTINE

Explore this box plot interactively →