OR9G1

Across TCGA cell cohorts, OR9G1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR9G1-associated genes across cancer lineages are CPLX4, KRTAP13-4, and DMRTB1. Each is linked with OR9G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR9G1-to-partner and partner-to-OR9G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CPLX4 grouped by OR9G1-low versus OR9G1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9G1→partner) and Y-score (partner→OR9G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CPLX4 →	+0.044	+4.392	<.001	.004	3	1
OVARY	KRTAP13-4 →	+0.028	+4.222	<.001	.006	3	1
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1L3 →	+0.028	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.036	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	SPINK8 →	+0.438	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

CPLX4 by OR9G1 expression — LARGE_INTESTINE

Explore this box plot interactively →