OR9A4

Across TCGA cell cohorts, OR9A4 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR9A4-associated genes across cancer lineages are OR14A16, OR8B3, and MEP1A. Each is linked with OR9A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR9A4-to-partner and partner-to-OR9A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR14A16 grouped by OR9A4-low versus OR9A4-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9A4→partner) and Y-score (partner→OR9A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR14A16 →	+0.032	+5.321	<.001	.005	3	1
CNS	OR8B3 →	+0.037	+4.981	<.001	.008	3	1
SKIN	MEP1A →	+0.082	+4.099	<.001	.008	3	1
SKIN	DEFA1 →	+0.347	+4.099	<.001	<.001	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.022	+5.539	<.001	.003	3	1
LARGE_INTESTINE	ZNF831 →	+0.011	+3.103	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR14A16 by OR9A4 expression — CNS

Explore this box plot interactively →