OR9A2

Across TCGA cell cohorts, OR9A2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR9A2-associated genes across cancer lineages are LYZL2, SMCP, and PSG6. Each is linked with OR9A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR9A2-to-partner and partner-to-OR9A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LYZL2 grouped by OR9A2-low versus OR9A2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR9A2→partner) and Y-score (partner→OR9A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	LYZL2 →	+0.016	+4.058	<.001	.007	3	1
LUNG_SCLC	SMCP →	+0.038	+4.058	<.001	.007	3	1
LUNG_SCLC	PSG6 →	+0.065	+3.523	<.001	.008	3	1
LUNG_SCLC	FBXO39 →	+0.021	+4.169	<.001	.001	3	1
LUNG_SCLC	SRARP →	+0.015	+4.684	<.001	<.001	3	1
LUNG_SCLC	CCDC196 →	+0.030	+3.736	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

LYZL2 by OR9A2 expression — LUNG_SCLC

Explore this box plot interactively →