Across TCGA pan-cancer cohorts, OR9A1P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR9A1P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where OR9A1P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR9A1P is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
KIRC, THCA, and KICH are the cancer types where OR9A1P tumor–normal differential expression is most reproducible.