OR8U1

Across TCGA pan-cancer cohorts, OR8U1 Mutation is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated OR8U1 data layer compared with 2 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR8U1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR8U1 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

COAD, SKCM, and LUSC are the cancer types where OR8U1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.131	0.803	<.001	48	view →
SKCM	DFS	Median	All	0.241	0.619	<.001	26	view →
LUSC	DFS	Median	All	0.161	0.712	.004	9	view →
BLCA	DFS	Median	All	1.000	0.327	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

OR8U1–COAD (OS)

Open the COAD breakdown →