OR8S21P

Across TCGA pan-cancer cohorts, OR8S21P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated OR8S21P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher OR8S21P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR8S21P expression acts as an unfavorable survival marker, although some lineages such as LUAD and ACC show a favorable association.

HNSC, MESO, and SKCM are the cancer types where OR8S21P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.234	0.713	.004	81	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
SKCM	OS	Tertile	All	0.162	0.781	<.001	54	view →
KIRP	OS	Tertile	II,III,IV	0.192	0.751	.004	42	view →
THYM	OS	Tertile	All	0.534	0.977	<.001	36	view →
CHOL	DFS	Tertile	All	0.045	0.497	.029	36	view →
ESCA	OS	Tertile	IV	0.135	0.568	.031	36	view →
COAD	DFS	Tertile	IV	0.037	0.495	<.001	36	view →
LUAD	OS	Tertile	All	0.845	0.660	.001	36	view →
UCEC	DFS	Tertile	IV	0.292	0.718	.021	30	view →
ACC	OS	Tertile	II,III,IV	0.972	0.804	.019	27	view →
STAD	OS	Tertile	III,IV	0.141	0.520	.004	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

OR8S21P–HNSC (OS)

Open the HNSC breakdown →