OR8S1

Across TCGA cell cohorts, OR8S1 RNA expression is significantly associated with the go_rna of many other GO terms, with 630 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible OR8S1-associated GO terms across cancer lineages are Regulation of apoptotic signaling pathway, Protein deubiquitination, and Negative regulation of programmed necrotic cell death. Each is linked with OR8S1 in more than 5 cancer types. Because this analysis shows association rather than direction, both OR8S1-to-partner and partner-to-OR8S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of apoptotic signaling pathway grouped by OR8S1-low versus OR8S1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8S1→partner) and Y-score (partner→OR8S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of apoptotic signaling pathway →	+0.051	+0.032	.001	.009	3	6
OVARY	Protein deubiquitination →	+0.036	+0.022	.002	.006	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of programmed necrotic cell death →	+0.074	+0.038	<.001	.004	3	5
OVARY	Endosomal transport →	+0.035	+0.015	.006	.006	3	4
LUNG_NSCLC_LUAD	Negative regulation of response to biotic stimulus →	+0.047	+0.027	.003	.009	2	5
LUNG_NSCLC_LUAD	Negative regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.047	+0.030	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 630 associations by consensus.

Regulation of apoptotic signaling pathway by OR8S1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →