OR8S1

Across TCGA cell cohorts, OR8S1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible OR8S1-associated genes across cancer lineages are CGB3, GABRA6, and RBMY1F. Each is linked with OR8S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8S1-to-partner and partner-to-OR8S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CGB3 grouped by OR8S1-low versus OR8S1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8S1→partner) and Y-score (partner→OR8S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CGB3 →	+0.236	+3.920	<.001	.005	3	1
SKIN	GABRA6 →	+0.103	+3.684	<.001	.006	3	1
SKIN	RBMY1F →	+0.052	+4.437	<.001	.004	3	1
SKIN	CXorf51B →	+0.933	+3.684	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CGB3 by OR8S1 expression — SKIN

Explore this box plot interactively →