OR8S1

Across TCGA cell cohorts, OR8S1 mutation is significantly associated with the mutation status of many other genes, with 488 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR8S1-associated genes across cancer lineages are LEO1, OR2T3, and SAMD9. Each is linked with OR8S1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8S1-to-partner and partner-to-OR8S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LEO1 grouped by OR8S1-low versus OR8S1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8S1→partner) and Y-score (partner→OR8S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	LEO1 →	+4.772	+5.339	.004	.004	1	3
CNS	OR2T3 →	+4.044	+5.000	.008	.008	1	2
CNS	SAMD9 →	+4.044	+5.000	.008	.008	1	2
SKIN	WDR97 →	+3.450	+4.133	<.001	<.001	1	2
LUNG_NSCLC_LUAD	HOXB9 →	+4.187	+5.000	.008	.008	1	2
LUNG_NSCLC_LUAD	INTS10 →	+4.187	+5.000	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 488 associations by consensus.

LEO1 by OR8S1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →