OR8R1P

Across TCGA pan-cancer cohorts, OR8R1P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of OR8R1P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OR8R1P RNA is repressed in tumor relative to normal tissue. In most cancer types OR8R1P is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

HNSC, BLCA, and THCA are the cancer types where OR8R1P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR8R1P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	−0.182	.001	6	view →
BLCA	Male	All	+0.262	.007	3	view →
THCA	Female	All	+0.119	.030	2	view →
UCEC	All	All	+0.110	.026	2	view →
LUSC	Female	III,IV	+0.130	.005	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

OR8R1P–HNSC

Open the HNSC breakdown →