OR8K5

Across TCGA patient cohorts, OR8K5 mutation is significantly associated with the RNA expression of many other genes, with 1,851 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8K5-associated genes across cancer lineages are ERVH-1, ENO2, and CDC20. Each is linked with OR8K5 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR8K5-to-partner and partner-to-OR8K5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERVH-1 grouped by OR8K5-low versus OR8K5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8K5→partner) and Y-score (partner→OR8K5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ERVH-1 →	+0.182	+2.097	.006	.001	3	3
SKCM	ENO2 →	+1.037	+1.867	.001	.005	3	3
SKCM	CDC20 →	+0.713	+2.018	.001	.005	3	3
SKCM	CNRIP1 →	-0.710	-2.797	.008	.003	3	3
UCEC	RAD54L →	+0.876	+2.828	<.001	.001	3	3
UCEC	CORO2B →	-0.639	-3.584	.009	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,851 associations by consensus.

ERVH-1 by OR8K5 expression — SKCM

Explore this box plot interactively →