OR8K3

Across TCGA cell cohorts, OR8K3 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible OR8K3-associated genes across cancer lineages are TRIM49, GABRG3, and CCDC177. Each is linked with OR8K3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8K3-to-partner and partner-to-OR8K3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM49 grouped by OR8K3-low versus OR8K3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8K3→partner) and Y-score (partner→OR8K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRIM49 →	+0.015	+3.930	<.001	.003	3	1
LARGE_INTESTINE	GABRG3 →	+0.350	+4.054	<.001	.004	3	1
LARGE_INTESTINE	CCDC177 →	+0.068	+4.076	<.001	.008	3	1
BLOOD_Lymphoma	PAX1 →	+0.646	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR2T12 →	+0.006	+5.643	.003	.002	3	1
BLOOD_Lymphoma	OR2AJ1 →	+0.042	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TRIM49 by OR8K3 expression — LARGE_INTESTINE

Explore this box plot interactively →