OR8K1

Across TCGA pan-cancer cohorts, OR8K1 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated OR8K1 data layer compared with 6 for mutation status.

The strongest signal is observed in small cell lung cancer (SCLC), where higher OR8K1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR8K1 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

SCLC, BLCA, and HNSC are the cancer types where OR8K1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Tertile	II,III,IV	0.164	0.819	<.001	54	view →
BLCA	DFS	Tertile	All	0.173	0.521	.010	36	view →
HNSC	DFS	Tertile	III,IV	0.257	0.624	.005	36	view →
LGG	OS	Tertile	All	0.714	0.899	<.001	33	view →
THCA	OS	Tertile	II,III,IV	0.589	0.903	.016	21	view →
THYM	DFS	Tertile	All	0.107	0.872	<.001	18	view →
KIRC	OS	Tertile	All	0.439	0.642	.015	12	view →
ESCA	OS	Tertile	III,IV	0.852	0.368	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

OR8K1–SCLC (OS)

Open the SCLC breakdown →