OR8J3

Across TCGA patient cohorts, OR8J3 mutation is significantly associated with the RNA expression of many other genes, with 2,192 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8J3-associated genes across cancer lineages are OIP5, PDCD2L, and RAD51. Each is linked with OR8J3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR8J3-to-partner and partner-to-OR8J3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by OR8J3-low versus OR8J3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8J3→partner) and Y-score (partner→OR8J3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OIP5 →	+0.736	+2.150	<.001	.009	3	4
LUAD	PDCD2L →	+0.682	+2.193	<.001	.001	3	4
UCEC	RAD51 →	+0.646	+2.258	.001	.001	3	4
LUAD	SNRPD3 →	+0.434	+1.800	<.001	.008	3	3
LUAD	COQ3 →	+0.399	+1.789	.001	.008	3	3
LUAD	CD1C →	-1.050	-2.898	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,192 associations by consensus.

OIP5 by OR8J3 expression — LUAD

Explore this box plot interactively →