OR8J3

Across TCGA cell cohorts, OR8J3 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR8J3-associated genes across cancer lineages are ASB17, ENPP6, and PROP1. Each is linked with OR8J3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8J3-to-partner and partner-to-OR8J3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by OR8J3-low versus OR8J3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8J3→partner) and Y-score (partner→OR8J3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ASB17 →	+0.029	+4.662	<.001	.005	3	2
LARGE_INTESTINE	ENPP6 →	+0.051	+3.793	<.001	.007	3	1
LARGE_INTESTINE	PROP1 →	+0.036	+4.054	<.001	.004	3	1
SKIN	OR6C70 →	+0.045	+3.217	<.001	.006	3	1
SKIN	ZPBP2 →	+0.025	+4.047	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR9I1 →	+0.020	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ASB17 by OR8J3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →