OR8J1

Across TCGA patient cohorts, OR8J1 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8J1-associated genes across cancer lineages are PDCD4, PCNA, and Gab2. Each is linked with OR8J1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8J1-to-partner and partner-to-OR8J1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by OR8J1-low versus OR8J1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8J1→partner) and Y-score (partner→OR8J1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.499	-1.797	.003	.025	3	2
UCEC	PCNA →	+0.237	+1.847	.002	.008	3	2
LUAD	Gab2 →	+0.292	+3.000	.041	.035	2	2
LUAD	PEA-15 →	-0.201	-3.288	.036	.009	3	1
SKCM	Bak →	-0.212	-2.459	.044	.020	3	1
SKCM	c-Met_pY1235 →	-0.079	-3.157	.048	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

PDCD4 by OR8J1 expression — UCEC

Explore this box plot interactively →