OR8H3

Across TCGA cell cohorts, OR8H3 RNA expression is significantly associated with the mutation status of many other genes, with 17 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible OR8H3-associated genes across cancer lineages are ADAM29, ZNF665, and DICER1. Each is linked with OR8H3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8H3-to-partner and partner-to-OR8H3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM29 grouped by OR8H3-low versus OR8H3-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8H3→partner) and Y-score (partner→OR8H3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADAM29 →	+3.984	+0.013	.006	<.001	3	1
BLOOD_Leukemia	ZNF665 →	+5.569	+0.027	.001	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	DICER1 →	+4.357	+0.087	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	YLPM1 →	+4.357	+0.087	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	PZP →	+4.357	+0.087	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	CNOT6L →	+5.357	+0.116	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

ADAM29 by OR8H3 expression — BLOOD_Leukemia

Explore this box plot interactively →