OR8H1

Across TCGA patient cohorts, OR8H1 mutation is significantly associated with the RNA expression of many other genes, with 3,401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8H1-associated genes across cancer lineages are SVIL-AS1, ZNF367, and MIR7159. Each is linked with OR8H1 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR8H1-to-partner and partner-to-OR8H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SVIL-AS1 grouped by OR8H1-low versus OR8H1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8H1→partner) and Y-score (partner→OR8H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SVIL-AS1 →	+0.457	+3.818	<.001	<.001	3	4
UCEC	ZNF367 →	+0.612	+1.847	.003	.009	3	4
LIHC	MIR7159 →	+0.318	+5.091	<.001	.003	3	3
UCEC	RNA5SP411 →	+1.170	+2.015	<.001	.001	3	3
UCEC	OIP5 →	+0.976	+2.758	<.001	<.001	3	3
SKCM	MVK →	+0.432	+2.682	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

SVIL-AS1 by OR8H1 expression — UCEC

Explore this box plot interactively →