OR8G2P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR8G2P mutation is significantly associated with the RNA expression of many other genes, with 998 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8G2P-associated genes across cancer lineages are PEF1, ZNF367, and OR5D3P. Each is linked with OR8G2P in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8G2P-to-partner and partner-to-OR8G2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PEF1 grouped by OR8G2P-low versus OR8G2P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8G2P→partner) and Y-score (partner→OR8G2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMPEF1 →+0.368+2.270<.001.00533
SKCMZNF367 →+0.608+3.384.005.00433
COADOR5D3P →+0.055+4.917.001.00332
COADRNU6-572P →+0.313+6.741<.001<.00132
UCECNDUFV2P1 →+0.681+2.606<.001.00632
UCECMVD →+0.794+3.370<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 998 associations by consensus.

PEF1 by OR8G2P expression — SKCM

Box plot of PEF1 in OR8G2P-low vs OR8G2P-high samples in SKCM.

Explore this box plot interactively →

Exploration