Across TCGA patient cohorts, OR8G1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8G1-associated genes across cancer lineages are Notch1, p62 Lck ligand, and PCNA. Each is linked with OR8G1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8G1-to-partner and partner-to-OR8G1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8G1→partner) and Y-score (partner→OR8G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.271	+3.472	<.001	.002	3	1
UCEC	p62 Lck ligand →	+0.456	+3.179	.002	.010	3	1
UCEC	PCNA →	+0.220	+2.321	.029	.034	2	2
UCEC	Rad50 →	-0.223	-2.584	.049	.011	3	1
UCEC	BRD4 →	+0.275	+2.999	.027	.034	3	1
UCEC	4E-BP1 →	+0.347	+2.199	.006	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

OR8G1 survival (RNA) · tumor vs normal (RNA) · all OR8G1 data types