OR8D2

Across TCGA cell cohorts, OR8D2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR8D2-associated genes across cancer lineages are IL17REL, IFNA17, and OR1L1. Each is linked with OR8D2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8D2-to-partner and partner-to-OR8D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL17REL grouped by OR8D2-low versus OR8D2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8D2→partner) and Y-score (partner→OR8D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	IL17REL →	+0.025	+3.691	<.001	.009	3	1
SKIN	IFNA17 →	+0.014	+3.345	<.001	.007	3	1
LARGE_INTESTINE	OR1L1 →	+0.029	+4.415	<.001	.007	3	1
LARGE_INTESTINE	C1orf68 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	LCE1F →	+0.106	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR12D2 →	+0.079	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

IL17REL by OR8D2 expression — SKIN

Explore this box plot interactively →