OR8D2

Across TCGA cell cohorts, OR8D2 mutation is significantly associated with the mutation status of many other genes, with 1,541 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible OR8D2-associated genes across cancer lineages are AGAP1, ADCY2, and DLGAP4. Each is linked with OR8D2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR8D2-to-partner and partner-to-OR8D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AGAP1 grouped by OR8D2-low versus OR8D2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8D2→partner) and Y-score (partner→OR8D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	AGAP1 →	+4.415	+4.977	.007	.007	1	4
LARGE_INTESTINE	ADCY2 →	+2.043	+3.693	.009	.009	1	3
LARGE_INTESTINE	DLGAP4 →	+2.284	+3.925	.005	.005	1	3
BLOOD_Leukemia	TRIM9 →	+4.309	+4.560	.007	.007	1	3
LUNG_NSCLC_LUAD	GRAMD1B →	+5.339	+4.772	.004	.004	1	3
OVARY	FAM83B →	+5.415	+5.415	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,541 associations by consensus.

AGAP1 by OR8D2 expression — OVARY

Explore this box plot interactively →