Across TCGA pan-cancer cohorts, OR8B7P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR8B7P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where OR8B7P RNA is repressed in tumor relative to normal tissue. In most cancer types OR8B7P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA and KIRC are the cancer types where OR8B7P tumor–normal differential expression is most reproducible.