Across TCGA patient cohorts, OR8A1 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR8A1-associated genes across cancer lineages are FOXO3a_pS318_S321, GSK-3a-b_pS21_S9, and MEK1_p_S217_S221. Each is linked with OR8A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8A1-to-partner and partner-to-OR8A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8A1→partner) and Y-score (partner→OR8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	+0.124	+3.009	.039	.019	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.432	+2.459	.036	.020	3	1
UCEC	MEK1_p_S217_S221 →	+0.281	+3.000	.033	.036	3	1
UCEC	Annexin-1 →	+0.517	+2.827	.042	.035	3	1
UCEC	Tuberin_pT1462 →	+0.375	+3.584	<.001	.002	3	1
UCEC	Caspase-8 →	-0.264	-3.295	.030	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

OR8A1 survival (RNA) · tumor vs normal (RNA) · all OR8A1 data types