Across TCGA cell cohorts, OR8A1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR8A1-associated genes across cancer lineages are OR2V2, PRAMEF20, and FAM205A. Each is linked with OR8A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR8A1-to-partner and partner-to-OR8A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8A1→partner) and Y-score (partner→OR8A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2V2 →	+0.014	+3.510	<.001	.003	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	FAM205A →	+0.019	+3.766	.001	.004	3	1
LARGE_INTESTINE	ADAM7 →	+0.004	+3.345	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

OR8A1 survival (RNA) · tumor vs normal (RNA) · all OR8A1 data types